A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density

INTRODUCTION: Mammographic density is an established breast cancer risk factor with a strong genetic component and can be increased in women using menopausal hormone therapy (MHT). Here, we aimed to identify genetic variants that may modify the association between MHT use and mammographic density. M...

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Published in:Breast Cancer Res
Main Authors: Rudolph, Anja, Fasching, Peter A., Behrens, Sabine, Eilber, Ursula, Bolla, Manjeet K., Wang, Qin, Thompson, Deborah, Czene, Kamila, Brand, Judith S., Li, Jingmei, Scott, Christopher, Pankratz, V. Shane, Brandt, Kathleen, Hallberg, Emily, Olson, Janet E., Lee, Adam, Beckmann, Matthias W., Ekici, Arif B., Haeberle, Lothar, Maskarinec, Gertraud, Le Marchand, Loic, Schumacher, Fredrick, Milne, Roger L., Knight, Julia A., Apicella, Carmel, Southey, Melissa C., Kapuscinski, Miroslav K., Hopper, John L., Andrulis, Irene L., Giles, Graham G., Haiman, Christopher A., Khaw, Kay-Tee, Luben, Robert, Hall, Per, Pharoah, Paul D. P., Couch, Fergus J., Easton, Douglas F., dos-Santos-Silva, Isabel, Vachon, Celine, Chang-Claude, Jenny
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537547/
https://ncbi.nlm.nih.gov/pubmed/26275715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0625-9
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