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Solution phase dynamics of the DNA repair enzyme spore photoproduct lyase as probed by H/D exchange
Spore photoproduct lyase (SPL) catalyzes the repair of the UV lesion spore photoproduct (SP) in a reaction dependent on S-adenosyl-L-methionine (SAM). We have utilized H/D exchange to show that in the presence of SAM, a significant reduction in H/D exchange is observed upon binding SPTpT or undamage...
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537165/ https://ncbi.nlm.nih.gov/pubmed/24950428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.06.011 |
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