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Spore photoproduct within DNA is a surprisingly poor substrate for its designated repair enzyme – the spore photoproduct lyase
DNA repair enzymes typically recognize their substrate lesions with high affinity to ensure efficient lesion repair. In UV irradiated endospores, a special thymine dimer, 5-thyminyl-5,6-dihydrothymine, termed the spore photoproduct (SP), is the dominant DNA photolesion, which is rapidly repaired dur...
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| Published in: | DNA Repair (Amst) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654379/ https://ncbi.nlm.nih.gov/pubmed/28320593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.11.005 |
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