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Spore photoproduct within DNA is a surprisingly poor substrate for its designated repair enzyme – the spore photoproduct lyase

DNA repair enzymes typically recognize their substrate lesions with high affinity to ensure efficient lesion repair. In UV irradiated endospores, a special thymine dimer, 5-thyminyl-5,6-dihydrothymine, termed the spore photoproduct (SP), is the dominant DNA photolesion, which is rapidly repaired dur...

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Dades bibliogràfiques
Publicat a:DNA Repair (Amst)
Autors principals: Yang, Linlin, Jian, Yajun, Setlow, Peter, Li, Lei
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654379/
https://ncbi.nlm.nih.gov/pubmed/28320593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.11.005
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