Postnatal Exposure to a High Carbohydrate Diet Interferes Epigenetically with Thyroid Hormone Receptor Induction of the Adult Male Rat Skeletal Muscle Glucose Transporter Isoform 4 Expression

Early life nutritional intervention causes adult onset insulin resistance and obesity in rats. Thyroid hormone receptor (TR) in turn transcriptionally enhances skeletal muscle Glut4 expression. We tested the hypothesis that reduced circulating TSH and T4 concentrations encountered in postnatal (PN4-...

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Vydáno v:J Nutr Biochem
Hlavní autoři: Raychaudhuri, Nupur, Thamotharan, Shanthie, Srinivasan, Malathi, Mahmood, Saleh, Patel, Mulchand S., Devaskar, Sherin U.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537062/
https://ncbi.nlm.nih.gov/pubmed/25086780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2014.05.011
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