Enhanced tumorigenicity by mitochondrial DNA mild mutations

To understand how mitochondria are involved in malignant transformation we have generated a collection of transmitochondrial cybrid cell lines on the same nuclear background (143B) but with mutant mitochondrial DNA (mtDNA) variants with different degrees of pathogenicity. These include the severe mu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cruz-Bermúdez, Alberto, Vallejo, Carmen G., Vicente-Blanco, Ramiro J., Gallardo, María Esther, Fernández-Moreno, Miguel Ángel, Quintanilla, Miguel, Garesse, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537038/
https://ncbi.nlm.nih.gov/pubmed/25909222
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