Efficacy of the antimicrobial peptide TP4 against Helicobacter pylori infection: in vitro membrane perturbation via micellization and in vivo suppression of host immune responses in a mouse model

Helicobacter pylori infection is marked by a strong association with various gastric diseases, including gastritis, ulcers, and gastric cancer. Antibiotic treatment regimens have low success rates due to the rapid occurrence of resistant H. pylori strains, necessitating the development of novel anti...

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Udgivet i:Oncotarget
Main Authors: Narayana, Jayaram Lakshmaiah, Huang, Han-Ning, Wu, Chang-Jer, Chen, Jyh-Yih
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper: Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536990/
https://ncbi.nlm.nih.gov/pubmed/26002554
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