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Nile Tilapia Derived Antimicrobial Peptide TP4 Exerts Antineoplastic Activity Through Microtubule Disruption

Some antimicrobial peptides (AMPs) exhibit anti-cancer activity, acting on cancer cells either by causing membrane lysis or via intracellular effects. While intracellular penetration of AMPs has been shown to cause cancer cell death, the mechanisms of toxicity remain largely unknown. Here we show th...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Ting, Chen-Hung, Liu, Yi-Chung, Lyu, Ping-Chiang, Chen, Jyh-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315541/
https://ncbi.nlm.nih.gov/pubmed/30469546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120462
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