Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage

Caenorhabditis elegans is an alternative in vivo model that is being successfully used to assess the pharmacological and toxic effects of drugs. The exponential growth of nanotechnology requires the use of alternative in vivo models to assess the toxic effects of theses nanomaterials. The use of pol...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Charão, Mariele Feiffer, Souto, Caroline, Brucker, Natália, Barth, Anelise, Jornada, Denise S, Fagundez, Daiandra, Ávila, Daiana Silva, Eifler-Lima, Vera L, Guterres, Silvia S, Pohlmann, Adriana R, Garcia, Solange Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536844/
https://ncbi.nlm.nih.gov/pubmed/26300641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S84909
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