Design of a randomized controlled trial of disclosing genomic risk of coronary heart disease: the Myocardial Infarction Genes (MI-GENES) study

BACKGROUND: Whether disclosure of a genetic risk score (GRS) for a common disease influences relevant clinical outcomes is unknown. We describe design of the Myocardial Infarction Genes (MI-GENES) Study, a randomized clinical trial to assess whether disclosing a GRS for coronary heart disease (CHD)...

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Detalles Bibliográficos
Publicado en:BMC Med Genomics
Main Authors: Kullo, Iftikhar J., Jouni, Hayan, Olson, Janet E., Montori, Victor M., Bailey, Kent R.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Study Protocol
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536729/
https://ncbi.nlm.nih.gov/pubmed/26271327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0122-0
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