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Differentiation of receptor subtypes by thermodynamic analysis: application to opioid delta receptors.

The temperature dependence of the dissociation constant for the interaction of an opioid delta selective ligand and its receptor was evaluated in three tissues. The change in free energy of this interaction was similar in mouse brain, mouse spinal cord, and NG 108-15 mouse neuroblastoma-rat glioma h...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wild, K D, Porreca, F, Yamamura, H I, Raffa, R B
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12018
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