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Deletion analysis of Streptococcus pneumoniae late competence genes distinguishes virulence determinants that are dependent or independent of competence induction

The competence regulon of Streptococcus pneumoniae (pneumococcus) is crucial for genetic transformation. During competence development, the alternative sigma factor ComX is activated, which in turn, initiates transcription of 80 “late” competence genes. Interestingly, only 16 late genes are essentia...

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Библиографические подробности
Опубликовано в: :Mol Microbiol
Главные авторы: Zhu, Luchang, Lin, Jingjun, Kuang, Zhizhou, Vidal, Jorge E., Lau, Gee W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536566/
https://ncbi.nlm.nih.gov/pubmed/25846124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13016
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