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Competence-Independent Activity of Pneumococcal Enda Mediates Degradation of Extracellular DNA and Nets and Is Important for Virulence

Membrane surface localized endonuclease EndA of the pulmonary pathogen Streptococcus pneumoniae (pneumococcus) is required for both genetic transformation and virulence. Pneumococcus expresses EndA during growth. However, it has been reported that EndA has no access to external DNA when pneumococcal...

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Detalhes bibliográficos
Main Authors: Zhu, Luchang, Kuang, Zhizhou, Wilson, Brenda A., Lau, Gee W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729463/
https://ncbi.nlm.nih.gov/pubmed/23936195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070363
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