Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy

It has been suggested that autophagy protects renal tubular epithelial cells (TECs) from injury in diabetic nephropathy (DN). However, the manner in which the autophagy-lysosome pathway is changed in this state remains unclear. In this study of DN, we investigated the autophagic activity and lysosom...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Wei Jing, Shen, Ting Ting, Chen, Rui Hong, Wu, Hong-Luan, Wang, Yan Jin, Deng, Jian Kun, Chen, Qiu Hua, Pan, Qingjun, Huang Fu, Chang-mei, Tao, Jing-li, Liang, Dong, Liu, Hua-feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536455/
https://ncbi.nlm.nih.gov/pubmed/26100632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666354
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