Transcription Factor PAX6 (Paired Box 6) Controls Limbal Stem Cell Lineage in Development and Disease

PAX6 is a master regulatory gene involved in neuronal cell fate specification. It also plays a critical role in early eye field and subsequent limbal stem cell (LSC) determination during eye development. Defects in Pax6 cause aniridia and LSC deficiency in humans and the Sey (Small eye) phenotype in...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Gen, Xu, Fan, Zhu, Jie, Krawczyk, Michal, Zhang, Ying, Yuan, Jin, Patel, Sherrinal, Wang, Yujuan, Lin, Ying, Zhang, Ming, Cai, Huimin, Chen, Daniel, Zhang, Meixia, Cao, Guiqun, Yeh, Emily, Lin, Danni, Su, Qiao, Li, Wen-wen, Sen, George L., Afshari, Natalie, Chen, Shaochen, Maas, Richard L., Fu, Xiang-Dong, Zhang, Kang, Liu, Yizhi, Ouyang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536450/
https://ncbi.nlm.nih.gov/pubmed/26045558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662940
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