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Pax 6 Controls Neural Crest Potential of Limbal Niche Cells to Support Self-Renewal of Limbal Epithelial Stem Cells

On ocular surface, corneal epithelial stem cells (SC) reside in limbus between cornea and conjunctiva. Pax6, an evolutionally conserved transcription factor essential for eye development, is expressed in post-natal corneal and limbal epithelia progenitors (LEPC) but not in underlying stroma. Because...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Chen, Szu-Yu, Cheng, Anny M. S., Zhang, Yuan, Zhu, Ying-Ting, He, Hua, Mahabole, Megha, Tseng, Scheffer C. G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611810/
https://ncbi.nlm.nih.gov/pubmed/31278274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45100-7
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