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Macroscopic modeling of mammalian cell growth and metabolism

We review major modeling strategies and methods to understand and simulate the macroscopic behavior of mammalian cells. These strategies comprise two important steps: the first step is to identify stoichiometric relationships for the cultured cells connecting the extracellular inputs and outputs. In...

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Publicado en:Appl Microbiol Biotechnol
Main Authors: Ben Yahia, Bassem, Malphettes, Laetitia, Heinzle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536272/
https://ncbi.nlm.nih.gov/pubmed/26198881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-015-6743-6
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