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IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells

Although IL-18 has not previously been shown to promote T lymphopoiesis, results obtained via a novel data mining algorithm (GAMMA), led us to explore a predicted role for this cytokine in T cell development. IL-18 is a member of the IL-1 cytokine family that has been extensively characterized as a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Gandhapudi, Siva K., Tan, Chibing, Marino, Julie H., Taylor, Ashlee A., Pack, Christopher C., Gaikwad, Joel, Van De Wiele, C. Justin, Wren, Jonathan D., Teague, T. Kent
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536257/
https://ncbi.nlm.nih.gov/pubmed/25780034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301542
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