Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation.

The 39- to 43-amino acid amyloid beta-protein (A beta), which is progressively deposited in cerebral plaques and blood vessels in Alzheimer disease (AD), is secreted by cultured human cells during normal metabolism. In studies of cell lines transfected with beta-amyloid precursor protein (beta APP)...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Citron, M, Vigo-Pelfrey, C, Teplow, D B, Miller, C, Schenk, D, Johnston, J, Winblad, B, Venizelos, N, Lannfelt, L, Selkoe, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.11993
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!