MicroRNA-144 dysregulates TGFβ signaling cascade and contributes to development of BOS following human lung transplantation

BACKGROUND: Bronchiolitis Obliterans Syndrome (BOS), chronic lung allograft rejection, remains an impediment for the function of the transplanted organ. In this study, we defined the role of MicroRNAs (miRNAs) miR-144 in fibroproliferation leading to BOS. METHODS: Biopsies were obtained from lung tr...

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Detalhes bibliográficos
Publicado no:J Heart Lung Transplant
Main Authors: Xu, Zhongping, Ramachandran, Sabarinathan, Gunasekaran, Muthukumar, Zhou, Fangyu, Trulock, Elbert, Kreisel, Daniel, Hachem, Ramsey, Mohanakumar, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536097/
https://ncbi.nlm.nih.gov/pubmed/25979625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2015.03.021
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