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Integrative Analysis of MicroRNA and mRNA Data Reveals an Orchestrated Function of MicroRNAs in Skeletal Myocyte Differentiation in Response to TNF-α or IGF1

INTRODUCTION: Skeletal muscle cell differentiation is impaired by elevated levels of the inflammatory cytokine tumor necrosis factor-α (TNF-α) with pathological significance in chronic diseases or inherited muscle disorders. Insulin like growth factor-1 (IGF1) positively regulates muscle cell differ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Meyer, Swanhild U., Sass, Steffen, Mueller, Nikola S., Krebs, Stefan, Bauersachs, Stefan, Kaiser, Sebastian, Blum, Helmut, Thirion, Christian, Krause, Sabine, Theis, Fabian J., Pfaffl, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536022/
https://ncbi.nlm.nih.gov/pubmed/26270642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135284
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