Profound Effect of Profiling Platform and Normalization Strategy on Detection of Differentially Expressed MicroRNAs – A Comparative Study

BACKGROUND: Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations. Thus, we investigated the impact of seven different...

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Bibliografiska uppgifter
Huvudupphovsmän: Meyer, Swanhild U., Kaiser, Sebastian, Wagner, Carola, Thirion, Christian, Pfaffl, Michael W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377731/
https://ncbi.nlm.nih.gov/pubmed/22723911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038946
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