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Destabilizing DNA during Rejoining Enhances Fidelity of Repair

A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.

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Detalhes bibliográficos
Publicado no:PLoS Biol
Autor principal: Robinson, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535887/
https://ncbi.nlm.nih.gov/pubmed/26271078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002214
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