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DNA mismatch repair efficiency and fidelity are elevated during DNA synthesis in human cells

DNA mismatch repair (MMR) within human cells is hypothesized to occur primarily at the replication fork. However, experimental models measuring MMR activity at specific phases of the cell cycle and during genomic DNA synthesis are lacking. We have investigated MMR activity within the nuclear environ...

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Detalhes bibliográficos
Main Authors: Edelbrock, Michael A., Kaliyaperumal, Saravanan, Williams, Kandace J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649689/
https://ncbi.nlm.nih.gov/pubmed/19138690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2008.12.006
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