Deep hypothermia for the treatment of refractory status epilepticus

In a rat model of status epilepticus (SE) induced by lithium and pilocarpine and refractory to midazolam, deep hypothermia (20°C for 30 min.) reduced EEG power over 50-fold, stopped SE within 12 minutes, and reduced EEG spikes by 87%. Hypothermia deserves further investigation as a treatment of last...

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Bibliografiske detaljer
Udgivet i:Epilepsy Behav
Main Authors: Niquet, Jerome, Baldwin, Roger, Gezalian, Michael, Wasterlain, Claude G.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535418/
https://ncbi.nlm.nih.gov/pubmed/26198217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2015.06.028
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