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Palliative chemotherapy followed by methylation inhibitor in high-risk acute myeloid leukemia: An in vitro and clinical study

Decitabine (5-aza-2′-deoxycytidine; DAC) is a well-tolerated alternative to aggressive chemotherapy for leukemia, which induces differentiation and apoptosis of leukemic cells as a DNA hypomethylating agent. The aim of the present study was to investigate the feasibility of DAC sequentially combined...

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Detalhes bibliográficos
Publicado no:Mol Clin Oncol
Main Authors: DING, BINGJIE, WANG, ZHIXIANG, JIANG, XUEJIE, LI, XIAODONG, WANG, CHUNLI, ZHONG, QINGXIU, JIANG, LING, DAI, MIN, ZHANG, YU, WEI, QI, MENG, FANYI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534877/
https://ncbi.nlm.nih.gov/pubmed/26623066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2015.605
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