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Endotoxemia-mediated inflammation potentiates aminoglycoside-induced ototoxicity
The ototoxic aminoglycoside antibiotics are essential to treat severe bacterial infections, particularly in neonatal intensive care units. Using a bacterial lipopolysaccharide (LPS) experimental model of sepsis, we tested whether LPS-mediated inflammation potentiates cochlear uptake of aminoglycosid...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534720/ https://ncbi.nlm.nih.gov/pubmed/26223301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac5546 |
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