Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens

Antibiotic resistance poses an increasingly grave threat to the public health. Of pressing concern, rapid spread of carbapenem-resistance among multidrug-resistant (MDR) Gram-negative rods (GNR) is associated with few treatment options and high mortality rates. Current antibiotic susceptibility test...

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Vydáno v:EBioMedicine
Hlavní autoři: Lin, Leo, Nonejuie, Poochit, Munguia, Jason, Hollands, Andrew, Olson, Joshua, Dam, Quang, Kumaraswamy, Monika, Rivera, Heriberto, Corriden, Ross, Rohde, Manfred, Hensler, Mary E., Burkart, Michael D., Pogliano, Joe, Sakoulas, George, Nizet, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534682/
https://ncbi.nlm.nih.gov/pubmed/26288841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.05.021
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