Role of CD4(+) Foxp3(+) Regulatory T Cells in Protection Induced by a Live Attenuated, Replicating Type I Vaccine Strain of Toxoplasma gondii

Vaccination with the live attenuated Toxoplasma gondii Mic1.3KO strain induced long-lasting immunity against challenge with Toxoplasma gondii type I and type II strains. The involvement of regulatory T cells (Tregs) in the protection mechanism was investigated. Intraperitoneal injection of Mic1.3KO...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Akbar, Haroon, Dimier-Poisson, Isabelle, Moiré, Nathalie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534668/
https://ncbi.nlm.nih.gov/pubmed/26123802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00217-15
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