Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection

Helminth infections are typically chronic in nature; however, the exact molecular mechanisms by which these parasites promote or thwart host immunity remain unclear. Worm expulsion requires the differentiation of CD4(+) T cells into Th2 cells, while regulatory T cells (Tregs) act to dampen the exten...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Mosconi, Ilaria, Dubey, Lalit Kumar, Volpe, Beatrice, Esser-von Bieren, Julia, Zaiss, Mario M., Lebon, Luc, Massacand, Joanna C., Harris, Nicola L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534664/
https://ncbi.nlm.nih.gov/pubmed/26150538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00266-15
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