Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against challenge infections with intestinal helmint...

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Hoofdauteurs: Esser-von Bieren, Julia, Mosconi, Ilaria, Guiet, Romain, Piersgilli, Alessandra, Volpe, Beatrice, Chen, Fei, Gause, William C., Seitz, Arne, Verbeek, J. Sjef, Harris, Nicola L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828184/
https://ncbi.nlm.nih.gov/pubmed/24244174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003771
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