Yüklüyor......
The RNA Helicase DHX34 Activates NMD by Promoting a Transition from the Surveillance to the Decay-Inducing Complex
Nonsense-mediated decay (NMD) is a surveillance mechanism that degrades aberrant mRNAs. A complex comprising SMG1, UPF1, and the translation termination factors eRF1 and eRF3 (SURF) is assembled in the vicinity of a premature termination codon. Subsequently, an interaction with UPF2, UPF3b, and the...
Kaydedildi:
| Yayımlandı: | Cell Rep |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2014
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534575/ https://ncbi.nlm.nih.gov/pubmed/25220460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.020 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|