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New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae

5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug, compromising its therapeutic action. The understanding of the underlying resistance mechanisms is crucial to deal with this problem. In this wo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Costa, Catarina, Ponte, Andreia, Pais, Pedro, Santos, Rui, Cavalheiro, Mafalda, Yaguchi, Takashi, Chibana, Hiroji, Teixeira, Miguel Cacho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534419/
https://ncbi.nlm.nih.gov/pubmed/26267134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135110
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