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Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord
Cell-free DNA shed by cancer cells has been shown to be a rich source of putative tumor-specific biomarkers. Because cell-free DNA from brain and spinal cord tumors cannot usually be detected in the blood, we studied whether the cerebrospinal fluid (CSF) that bathes the CNS is enriched for tumor DNA...
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Wydane w: | Proc Natl Acad Sci U S A |
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Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
National Academy of Sciences
2015
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534284/ https://ncbi.nlm.nih.gov/pubmed/26195750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511694112 |
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