Electron-capture dissociation and ion mobility mass spectrometry for characterization of the hemoglobin protein assembly

Native spray has the potential to probe biophysical properties of protein assemblies. Here we report an investigation using both ECD top-down sequencing with an FTICR mass spectrometer and ion mobility (IM) measurements on a Q-TOF to investigate the collisionally induced unfolding of a native-like h...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Cui, Weidong, Zhang, Hao, Blankenship, Robert E, Gross, Michael L
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Methods and Applications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534183/
https://ncbi.nlm.nih.gov/pubmed/26032343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2712
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