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H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes

Histone gene transcription is actively downregulated after completion of DNA synthesis to avoid overproduction. However, the precise mechanistic details of the cessation of histone mRNA synthesis are not clear. We found that histone H2B phosphorylation at Tyr37 occurs upstream of histone cluster 1,...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Mahajan, Kiran, Fang, Bin, Koomen, John M, Mahajan, Nupam P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533924/
https://ncbi.nlm.nih.gov/pubmed/22885324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2356
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