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Enzymatic Mechanism of Leishmania major Peroxidase and the Critical Role of Specific Ionic Interactions
Leishmania major peroxidase (LmP) is very similar to the well-known yeast cytochrome c peroxidase (CcP). Both enzymes catalyze the peroxidation of cytochrome c. Like CcP, LmP reacts with H(2)O(2) to form Compound I, which consists of a ferryl heme and a Trp radical, Fe(IV)= O;Trp(•+). Cytochrome c (...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533909/ https://ncbi.nlm.nih.gov/pubmed/25941976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00338 |
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