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CX3CL1 Promotes Breast Cancer via Transactivation of the EGF Pathway

Chemokines are relevant molecules in shaping the tumor microenvironment, although their contributions to tumorigenesis are not fully understood. We studied the influence of the chemokine CX3CL1/fractalkine in de novo breast cancer formation using HER2/neu transgenic mice. CX3CL1 expression was downm...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Tardáguila, Manuel, Mira, Emilia, García-Cabezas, Miguel A., Feijoo, Anna M., Quintela-Fandino, Miguel, Azcoitia, Iñigo, Lira, Sergio A., Mañes, Santos
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533861/
https://ncbi.nlm.nih.gov/pubmed/23720051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3828
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