DISTRIBUTION OF DOXORUBICIN IN RATS UNDERGOING ULTRASONIC DRUG DELIVERY

Ultrasound increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, ultrasound was used to deliver doxorubicin sequestered in micelles in an in vivo rat model with bilateral leg tumors. One of two frequencies with identical mechan...

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Bibliographic Details
Published in:J Pharm Sci
Main Authors: Staples, Bryant J., Pitt, William G., Roeder, Beverly L., Husseini, Ghaleb A., Rajeev, Deepthi, Schaalje, G. Bruce
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533826/
https://ncbi.nlm.nih.gov/pubmed/20166203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22088
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