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DISTRIBUTION OF DOXORUBICIN IN RATS UNDERGOING ULTRASONIC DRUG DELIVERY

Ultrasound increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, ultrasound was used to deliver doxorubicin sequestered in micelles in an in vivo rat model with bilateral leg tumors. One of two frequencies with identical mechan...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Staples, Bryant J., Pitt, William G., Roeder, Beverly L., Husseini, Ghaleb A., Rajeev, Deepthi, Schaalje, G. Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533826/
https://ncbi.nlm.nih.gov/pubmed/20166203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22088
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