Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors

The epithelial-to-mesenchymal transition (EMT) is a well-known prerequisite for cancer cells to acquire the migratory and invasive capacity, and to subsequently metastasize. Bufalin is one of the major active components of the traditional Chinese medicine Chan Su, and accumulating evidence has shown...

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Bibliographic Details
Published in:	Int J Mol Med
Main Authors:	ZHAO, LEI, LIU, SHIZHOU, CHE, XIAOFANG, HOU, KEZUO, MA, YANJU, LI, CE, WEN, TI, FAN, YIBO, HU, XUEJUN, LIU, YUNPENG, QU, XIUJUAN
Format:	Artigo
Language:	Inglês
Published:	D.A. Spandidos 2015
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4533784/ https://ncbi.nlm.nih.gov/pubmed/26133118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2268
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Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors

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