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Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors
To identify peptides with high affinity and specificity against human epidermal growth factor receptor 2 (HER2), a series of peptides were designed based on the structure of HER2 and its Z(HER2:342) affibody. By using a combination protocol of molecular dynamics modeling, MM/GBSA binding free energy...
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| Wydane w: | Theranostics |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Ivyspring International Publisher
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533098/ https://ncbi.nlm.nih.gov/pubmed/26284145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.12398 |
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