Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a serious lung condition characterized by vascular remodeling in the precapillary pulmonary arterioles. We and others have demonstrated chromosomal abnormalities and increased DNA damage in PAH lung vascular cells, but their timing and role in dise...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Federici, Chiara, Drake, Kylie M., Rigelsky, Christina M., McNelly, Lauren N., Meade, Sirena L., Comhair, Suzy A. A., Erzurum, Serpil C., Aldred, Micheala A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532823/
https://ncbi.nlm.nih.gov/pubmed/25918951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201411-2128OC
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