Protection against live rotavirus challenge in mice induced by parenteral and mucosal delivery of VP6 subunit rotavirus vaccine

Live oral rotavirus (RV) vaccines are part of routine childhood immunization but are associated with adverse effects, particularly intussusception. We have developed a non-live combined RV – norovirus (NoV) vaccine candidate consisting of human RV inner-capsid rVP6 protein and NoV virus-like particl...

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Bibliografske podrobnosti
izdano v:Arch Virol
Main Authors: Lappalainen, Suvi, Pastor, Ana Ruth, Malm, Maria, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A., Vesikari, Timo, Blazevic, Vesna
Format: Artigo
Jezik:Inglês
Izdano: Springer Vienna 2015
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532722/
https://ncbi.nlm.nih.gov/pubmed/26016444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-015-2461-8
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