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Protection against live rotavirus challenge in mice induced by parenteral and mucosal delivery of VP6 subunit rotavirus vaccine

Live oral rotavirus (RV) vaccines are part of routine childhood immunization but are associated with adverse effects, particularly intussusception. We have developed a non-live combined RV – norovirus (NoV) vaccine candidate consisting of human RV inner-capsid rVP6 protein and NoV virus-like particl...

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Detalhes bibliográficos
Publicado no:Arch Virol
Main Authors: Lappalainen, Suvi, Pastor, Ana Ruth, Malm, Maria, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A., Vesikari, Timo, Blazevic, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532722/
https://ncbi.nlm.nih.gov/pubmed/26016444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-015-2461-8
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