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Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo

Rotavirus (RV) is a common cause of severe gastroenteritis (GE) in children worldwide. Live oral RV vaccines protect against severe RVGE, but the immune correlates of protection are not yet clearly defined. Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6...

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Bibliografiska uppgifter
Huvudupphovsmän: Lappalainen, Suvi, Pastor, Ana Ruth, Tamminen, Kirsi, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A, Vesikari, Timo, Blazevic, Vesna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186038/
https://ncbi.nlm.nih.gov/pubmed/25424814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28858
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