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Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo

Rotavirus (RV) is a common cause of severe gastroenteritis (GE) in children worldwide. Live oral RV vaccines protect against severe RVGE, but the immune correlates of protection are not yet clearly defined. Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6...

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Détails bibliographiques
Auteurs principaux: Lappalainen, Suvi, Pastor, Ana Ruth, Tamminen, Kirsi, López-Guerrero, Vanessa, Esquivel-Guadarrama, Fernando, Palomares, Laura A, Vesikari, Timo, Blazevic, Vesna
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186038/
https://ncbi.nlm.nih.gov/pubmed/25424814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28858
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