Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication

Telomeres, the ends of linear eukaryotic chromosomes, have a specialized chromatin structure that provides a stable chromosomal terminus. In budding yeast Rap1 protein binds to telomeric TG repeat and negatively regulates telomere length. Here we show that binding of multiple Rap1 proteins stimulate...

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發表在:PLoS Genet
Main Authors: Goto, Greicy H., Zencir, Sevil, Hirano, Yukinori, Ogi, Hiroo, Ivessa, Andreas, Sugimoto, Katsunori
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532487/
https://ncbi.nlm.nih.gov/pubmed/26263073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005283
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