Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance

BACKGROUND AND PURPOSE: Myocardial infarction leads to heart failure. Autophagy is excessively activated in myocardial ischemia/reperfusion (I/R) in rats. The aim of this study is to investigate whether the protection of sevoflurane postconditioning (SPC) in myocardial I/R is through restored impair...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Peng, Zhang, Jing, Yu, Shuchun, Luo, Zhenzhong, Hua, Fuzhou, Yuan, Linhui, Zhou, Zhidong, Liu, Qin, Du, Xiaohong, Chen, Sisi, Zhang, Lieliang, Xu, Guohai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532466/
https://ncbi.nlm.nih.gov/pubmed/26263161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134666
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