Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro

It is well established that the secretion of thrombospondin-1 (TSP-1) by activated stromal cells and its accumulation in the tumor microenvironment during dysplasia inhibits primary tumor growth through inhibition of angiogenesis. This inhibitory function of TSP-1 is actuated either by inhibiting MM...

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Bibliographic Details
Published in:Discoveries (Craiova)
Main Authors: Ndishabandi, Dorothy, Duquette, Cameron, Billah, Ghita El-Moatassim, Reyes, Millys, Duquette, Mark, Lawler, Jack, Kazerounian, Shideh
Format: Artigo
Language:Inglês
Published: Applied Systems srl 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532438/
https://ncbi.nlm.nih.gov/pubmed/26273699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15190/d.2014.23
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