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Fluorescent Adenosine Analog as a Substrate for an A-to-I RNA Editing Enzyme
Adenosine to inosine RNA editing catalyzed by ADAR enzymes is common in humans and altered editing is associated with disease. Experiments using substrate RNAs with adenosine analogs at editing sites are useful for defining features of the ADAR reaction mechanism. Here we evaluated the reactivity of...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532316/ https://ncbi.nlm.nih.gov/pubmed/26095193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201502070 |
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