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Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging
We report a method for the sensitive detection of rare chromosome breaks and translocations in interphase cells. HiBA-FISH (High-throughput break-apart FISH) combines high-throughput imaging with the measurement of the spatial separation of FISH probes flanking target genome regions of interest. As...
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| Pubblicato in: | Genome Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4531802/ https://ncbi.nlm.nih.gov/pubmed/26313373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0718-x |
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